Dosing of metoprolol In geriatric patients can actually differ by age and by gender based on recent studies geriatric patients should be typed based on not just need bud gender as well.
Covid has put a strain on the assisted living in long-term care facility ecosystem but missing important information in dosing is more important now than ever before especially with the reduced staff and ability to manage problematic cases
Metoprolol Dosing for Geriatric patients in nursing homes modified by gender
Metoprolol doses resulting a similar AUC in a healthy young male administered 50mg tablet were 15mg for geriatric women and 25mg for geriatric men. Further, Metoprolol doses of 25mg for geriatric women and 50mg for geriatric men resulted in an equivalent AUC to a healthy young males dosed with a 100mg tablet. A 15mg Metoprolol tablet may need to be compounded to account for the gender differences in Metoprolol pharmacokinetics.Keywords: metoprolol, gender, geriatrics, population pharmacokinetics, monolix, does as seen on nih.gov
Find Oseen, data set and titration at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959610/