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Diabetes and COVID - Healthcare Quality Improvement Campaign
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Birth Defects from Metformin

A recent study of newborns found that men who were taking diabetes medication Metformin prior to conception were at a 40% increased chance of the baby being born with some type of birth defect. 

What is Metformin?

Metformin is a general name for this leading type of compound that is being manufactured by 6 brand name and 6 or more generic pharmaceutical companies leading the market, although the specific one or ones triggering the birth defects has not yet been made known.  

COVID Hospitalization and Diabetes

Recent studies have shown that men who were admitted to the ICU with COVID-19 developed a 400% greater risk of developing diabetes.  This implies that these men admitted to the ICU had developed IgM from the infection and not IgG. 

Diabetes Prevention Post COVID-19

This is key because if Antibody Test results would have been made known at the time to the patient, potential ongoing complications to the man and the child could perhaps have been prevented through vitamin or nutraceutical intervention to combat diagnosed and pre diabetes.

Diabetes and Pregnancy Risk

Diabetes and conception affect more than the father and the baby, it also affects the mother. Similarly, women with diagnosed diabetes prior to pregnancy were linked with nearly a 50% chance of the baby being born with a birth defect.

The defects in children born to women with diabetes are heart problems, brain and spinal defects, oral clefts, kidney and gastrointestinal tract defects, and limb deficiencies. There is not enough data to conclude the defects from men with diabetes, nor couples who both have diabetes.

Diabetes Incidence and Prevalence

The CDC report that adults with diagnosed diabetes found that around 69% had high blood pressure, 44% had high cholesterol, 39% had chronic kidney disease, and 12% reported having vision impairment or blindness.  Diabetes was highest among Black and Hispanic/Latino adults, in both men and women.

Diabetes and Rare Diseases

Currently 1 in 10 Americans have diabetes and NCBI predicts that Americans with prediabetes will jump from 90.6 million in 2015 to 107.7 million in 2030, and this stat does not take into account the newly diagnosed men post-covid.

However, it is also important to note that 1 in 10 Americans also have a rare disease with more than 50% of all rare diseases and mutations currently undiagnosed or misdiagnosed, and 90% of diagnosed rare diseases already without a treatment.  Today, rare diseases account for nearly $1.2 Trillion dollars out of the total $4.2 Trillion US GDP for healthcare spending. 

Rare Diseases in Children

Through a retrospective analysis of de-identified historical big data, AI and machine learning, we are projecting the number of new rare diseases resulting from birth complications to dramatically multiply in the coming years although it can be prevented through better understanding the data. As of 2022, the number of Americans with an undiagnosed rare disease is at an all-time high and growing each year with no treatments available specific to the child’s condition.  

The Pharmacies Role in a Post-Covid Era

A key player as we move forward will be independent pharmacies who are performing antigen and antibody testing because of their ability to service and treat entire families including mothers and infants. 

Long Term Effects of Diabetes and COVID

The issue we face as researchers is the difficulty in obtaining data for youth, particularly in the hospital setting. However, we must be creative because at this rate our healthcare GDP could nearly quadruple over the next decade when combined with the Medicare population which is growing around 7,000 people each day.

To browse diabetes and covid datasets, please click the link below

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